In Season 1, Meredith started an affair with Derek Shepherd, the flirtatious but wildly talented surgeon. Meredith thought he was her soul mate when the two began a forbidden sexual relationship - but now that the wife Meredith never knew he had arrives, she's not so sure. Preston Burke's arrogance is second only to his skill with a scalpel. He meets his match in Cristina when they begin a less romantic but equally forbidden relationship of their own - a relationship complicated by Cristina's refusal to reveal to Burke that she is pregnant with his child. Overseeing them all is Dr. Richard Webber, Seattle Grace's paternal but nononsense chief of surgery who harbors some secrets of his own concerning Meredith's mother.